yumC

yumC
168

ferredoxin/flavodoxin-NAD(P) oxidoreductase

locus
BSU_32110
Molecular weight
36.68 kDa
pI
5.57
Protein length
Gene length
function
redox reactions that involve ferredoxin and flavodoxin
product
ferredoxin/flavodoxin reductase
essential
yes
ec
1.18.1.2
synonyms
yumC

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0492 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,301,586 → 3,302,584
Phenotypes of a mutant
essential [Pubmed|12682299]
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The protein
Catalyzed reaction/ biological activity
H+ + NADP+ + 2 reduced [2Fe-2S]-[ferredoxin] --> NADPH + 2 oxidized [2Fe-2S]-[ferredoxin] (according to UniProt)
Protein family
ferredoxin--NADP reductase type 2 family (with [protein|C35A302F0B0BC724EC91B47AB4D38CF56CADD574|ycgT], according to UniProt)
[wiki|Cofactors]
FAD [Pubmed|20878669]
Structure
[PDB|3LZW]\t[Pubmed|20878669]
[AF|O05268]
Modification
active site Cys85 is S-bacillithiolated by NaOCl stress in ''B. subtilis'' and other ''Bacillus'' species [http://www.ncbi.nlm.nih.gov/pubmed/22938038  PubMed]
Paralogous protein(s)
[protein|C35A302F0B0BC724EC91B47AB4D38CF56CADD574|ycgT]
Expression and Regulation
Operons
genes
[gene|BAA74A6971CED9FB55540F1BC602CDA287D83E74|yumC]
description
[Pubmed|22383849]
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[gene|BAA74A6971CED9FB55540F1BC602CDA287D83E74|yumC]

2024-03-10 09:01:06

ghost

52

70818d4dc6c63b107e0d015ec64631b9903cf5f4

6A7D7DABBF652677EEF71E60C0E0B5E4B1E494B2

additional information
the mRNA is cleaved by [protein|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|RNase III] [PubMed|26883633]
Biological materials
Mutant
MGNA-B572 (yumC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1571 NBRP B. subtilis, Japan]
References
22938038,20208166,20878669,19162251,15252706,24529496,25194416,25698107,26507228,26965753,26883633,33591179,36700861,37760044

BAA74A6971CED9FB55540F1BC602CDA287D83E74

Page visits: 4407

Time of last update: 2024-03-28 19:37:48

Author of last update: Jstuelk