tpx

tpx
168

probable thiol peroxidase

locus
BSU_29490
Molecular weight
18.07 kDa
pI
4.7
Protein length
Gene length
function
unknown
product
unknown
essential
no
synonyms
tpx, ytgI

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2077 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,017,696  3,018,199
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The protein
Catalyzed reaction/ biological activity
[protein]-dithiol + hydroperoxide --> [protein]-disulfide + alcohol + H2O (according to UniProt)
Protein family
[wiki|peroxiredoxin family] (according to UniProt)
[wiki|Domains]
[wiki|Thioredoxin domain] (aa 18-167) (according to UniProt)
Structure
[PDB|2JSZ]
[AF|P80864]
Expression and Regulation
Operons
genes
[gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]-[gene|2C83EECFA809F34ADCA6445CF2E6BAC730D523DB|ytxK]
description
[Pubmed|22383849]
regulatory mechanism
[protein|2C6386E9A63F410558D168798D077DF91590F454|spx]: activation, [pubmed|12642660,19575568], in [regulon|protein:2C6386E9A63F410558D168798D077DF91590F454|spx regulon]
Open in new tab

[gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]→[gene|2C83EECFA809F34ADCA6445CF2E6BAC730D523DB|ytxK]

2024-03-11 09:08:17

Jstuelk

42

7fbd71a0dc51c44d0a5d6b85287eec2fe6db2d79

3F40B3FAFCCEFCAA3D5CE8250AA4915227F18104

genes
[gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]
description
[Pubmed|9387221]
regulatory mechanism
[protein|2C6386E9A63F410558D168798D077DF91590F454|spx]: activation, [Pubmed|12642660,19575568], in [regulon|protein:2C6386E9A63F410558D168798D077DF91590F454|spx regulon]
Open in new tab

[gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]

2024-03-11 09:04:15

ghost

42

39f441127623522a55edc7bb4ffe19aba6c89195

9C0F3827A1A8F8A92E28E2B9DF298EACAAD6F1E4

Biological materials
Mutant
MGNA-A113 (ytgI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/113 NBRP B. subtilis, Japan]
BKE29490 ([gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29490 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATAATTCCTCCCTTTT,  downstream forward: _UP4_TAAGCAGGGAAAAAAGCTCC
BKK29490 ([gene|2501228D435B151F151A3C0EF10DE99A8395977F|tpx]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29490 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATAATTCCTCCCTTTT,  downstream forward: _UP4_TAAGCAGGGAAAAAAGCTCC
References
36815589,19636900,9387221,12642660

2501228D435B151F151A3C0EF10DE99A8395977F

Page visits: 1708

Time of last update: 2024-03-28 01:37:03

Author of last update: Jstuelk