rnz

rnz
168

RNase Z

locus
BSU_23840
Molecular weight
33.87 kDa
pI
5.8
Protein length
Gene length
function
processing of CCA-less tRNA precursors
product
endoribonuclease Z
essential
yes
ec
3.1.26.11
synonyms
rnz, yqjK

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1234 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,478,006 → 2,478,929
Phenotypes of a mutant
essential [Pubmed|12682299]
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The protein
Catalyzed reaction/ biological activity
Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule (according to UniProt)
3' end maturation of tmRNA [Pubmed|25402410]
Protein family
[wiki|RNase] Z family (single member, according to UniProt)
Structure
[PDB|2FK6] (in complex with tRNA-Thr) [Pubmed|22940585],  [PDB|1Y44]
[AF|P54548]
Expression and Regulation
Operons
genes
[gene|C40C5D35ED53D343C8200248FCCB010BAB388054|rnz]-[gene|5189DF2F6144CD2429B5C01B1AD03BAE98307579|rpmGC]
description
[Pubmed|22383849]
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[gene|C40C5D35ED53D343C8200248FCCB010BAB388054|rnz]→[gene|5189DF2F6144CD2429B5C01B1AD03BAE98307579|rpmGC]

2024-02-17 00:51:21

Jstuelk

34

9b75b14da5e0fbcb61c2f1b51ed72e4db0129627

1CBCA9E007948AC48210D84174D287AD649FE23D

labs
[wiki|Ciaran Condon], IBPC, Paris, France [http://www.ibpc.fr/UPR9073/condon/index_en.html Homepage]
References
Reviews
19215776,17599240,25878039,31464530,35787606
Original Publications
17005971,12941704,15654328,16518398,22940585,25402410,24022488,31003868,36840557

C40C5D35ED53D343C8200248FCCB010BAB388054

Page visits: 1182

Time of last update: 2024-03-27 04:42:32

Author of last update: Jstuelk