pksM

168

polyketide synthase

locus: BSU_17200

Molecular weight: 475.31 kDa

pI: 5.31

Protein length: 4262 aa

Gene length: 12789 bp

function: polyketide synthesis

product: polyketide synthase

essential: no

ec: null

synonyms: pksM

List of homologs in different organisms, belongs to COG3321 (Galperin et al., 2021)

Gene

Coordinates: 1,821,553  1,834,341

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The protein

[wiki|Domains]

• 4 [wiki|Carrier domain]s (aa 293-367, aa 2188-2261, aa 3409-3486, aa 4135-4212) (according to UniProt)

Structure

• [PDB|6MHK] (from B. amyloliquefacies, corresponds to aa 395 ... 994, 2321 ... 2902, 3532 ... 4110, 73% identity)

Biological materials

Mutant

• BKE17200 ([gene|40779D3A6E4F72EEFD702BF9FA15B57951783D12|pksM]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE17200 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_AGTTATCATTTTCCCACTCC,  downstream forward: _UP4_TAAAGAAATTCTCGATGCCT
• BKK17200 ([gene|40779D3A6E4F72EEFD702BF9FA15B57951783D12|pksM]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK17200 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_AGTTATCATTTTCCCACTCC,  downstream forward: _UP4_TAAAGAAATTCTCGATGCCT

References

• 17190806,22383849,24187085