fliK

168

flagellar hook-length control, substrate specificity switch regulator

locus: BSU_16270

Molecular weight: 47.35 kDa

pI: 4.71

Protein length: 487 aa

Gene length: 1464 bp

function: movement and chemotaxis

product: flagellar hook-length control

essential: no

synonyms: fliK

List of homologs in different organisms, belongs to COG3144 (Galperin et al., 2021)

Gene

Coordinates: 1,698,278  1,699,741

Phenotypes of a mutant

• inactivation of ''[gene|42277DE1030E6FEB416EAE381CD40A54D49736FF|fliK]'' confers resistance to high concentrations of Zn(II) [Pubmed|27935957]
• no secretion of [protein|F03144BF8A187C8931938A21433431B8961E8EE7|flgM], permanent inhibition of [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|sigD] [Pubmed|25313396]
• defective in [category|SW.4.1.4|Swarming] motility [pubmed|35638827]

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The protein

Protein family

• FliK family (single member, according to UniProt)

Structure

• [AF|P23451]

[wiki|Localization]

• flagellum hook (according to UniProt)

Biological materials

Mutant

• BKE16270 ([gene|42277DE1030E6FEB416EAE381CD40A54D49736FF|fliK]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE16270 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACCTTTCATTCCCCCTATT,  downstream forward: _UP4_GAATGACTTCTATAAGTTCA
• BKK16270 ([gene|42277DE1030E6FEB416EAE381CD40A54D49736FF|fliK]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK16270 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CACCTTTCATTCCCCCTATT,  downstream forward: _UP4_GAATGACTTCTATAAGTTCA

References

Reviews

• 26490009

Original Publications

• 14651647,9657996,8157612,15175317,17850253,25313396,24386445,27935957,35638827