thiV
168
thiamine [wiki|ECF transporter] (membrane protein, thiamine-specific S protein)
locus
BSU_13230
Molecular weight
21.02 kDa
pI
9.89
function
thiamine uptake
product
thiamine [wiki|ECF transporter] (membrane protein, thiamine-specific S protein)
essential
no
synonyms
thiV, ykoE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4721 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,390,439 1,391,038
The protein
Structure
[PDB|5EDL] [pubmed|27447050]
[AF|O34738]
[wiki|Localization]
membrane associated [Pubmed|18763711]
Expression and Regulation
Operons
genes
[gene|57A953B5D71F3FD8269EAF2366B8E2C7A8C79483|thiU]-[gene|9AF27E4CE34B5C4036840A27D93B13213E3324DD|thiV]-[gene|EF69891D9CF0CE57367B38FB3C69DDE1B689FCB7|thiW]-[gene|236095EDE02EC9EA7768D9D30CED2345D3B7A1A9|thiX]
description
[Pubmed|16291685]
regulation
repressed by thiamine ([protein|search|Thi-box]) [Pubmed|12376536]
regulatory mechanism
[protein|E195900D971AEE4A790D4579BE5E5A15B81010B8|Thi-box]: RNA switch, via [wiki|RNA switch], in [regulon|protein:E195900D971AEE4A790D4579BE5E5A15B81010B8|Thi-box regulon]
Biological materials
Mutant
MGNA-A756 (ykoE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/756 NBRP B. subtilis, Japan]
BKE13230 ([gene|9AF27E4CE34B5C4036840A27D93B13213E3324DD|thiV]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE13230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTCTTTTACTTTCCAGCTTT, downstream forward: _UP4_AAGAAACGGAAGCGGGCGTC
BKK13230 ([gene|9AF27E4CE34B5C4036840A27D93B13213E3324DD|thiV]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK13230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTCTTTTACTTTCCAGCTTT, downstream forward: _UP4_AAGAAACGGAAGCGGGCGTC
References
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Time of last update: 2024-04-19 17:33:30
Author of last update: Jstuelk