yitG

168

similar to multidrug resistance protein

locus: BSU_10980

Molecular weight: 45.35 kDa

pI: 9.74

Protein length: 422 aa

Gene length: 1269 bp

function: unknown

product: unknown

essential: no

synonyms: yitG

List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)

Gene

Coordinates: 1,175,985 → 1,177,253

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The protein

Protein family

• [wiki|major facilitator superfamily] (according to UniProt)

Structure

• [AF|Q796Q1]

[wiki|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|BA1A7ECAE0B5690F6E6A67785BAB18628701E2A2|yitG]-[gene|F1A84EC28BE0E306356A331FD362E3CDAE49A3AB|yitF]

  description: [Pubmed|16497325]

  regulation

  • expressed during sporulation in the forespore ([protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]) [Pubmed|16497325,15699190]

  sigma factors

  • [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|16497325,15699190], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]

additional information

• [protein|search|translation] is likely to require [protein|3054CD45713BBD69C2A528DE24AF6AF37175FD9D|efp] due to the presence of several consecutive proline residues [PubMed|23239624,23239623]

Biological materials

Mutant

• MGNA-B181 (yitG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1180 NBRP B. subtilis, Japan]
• BKE10980 (Δ[gene|BA1A7ECAE0B5690F6E6A67785BAB18628701E2A2|yitG]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10980 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTCAGAGCACACTCCTT,  downstream forward: _UP4_GCTGAGGAAAGGTAGCACCC
• BKK10980 (Δ[gene|BA1A7ECAE0B5690F6E6A67785BAB18628701E2A2|yitG]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10980 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTCAGAGCACACTCCTT,  downstream forward: _UP4_GCTGAGGAAAGGTAGCACCC

References

• 16497325,15699190,10960106