yhgD

168

similar to transcriptional regulator ([wiki|TetR family])

locus: BSU_10150

Molecular weight: 21.65 kDa

pI: 7.24

Protein length: 191 aa

Gene length: 576 bp

function: unknown

product: unknown

essential: no

synonyms: yhgD, yixD

List of homologs in different organisms, belongs to COG1309 (Galperin et al., 2021)

Gene

Coordinates: 1,089,755  1,090,330

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The protein

Protein family

• [wiki|TetR family]

[wiki|Domains]

• [wiki|HTH tetR-type domain] (aa 3-63) (according to UniProt)

Structure

• [PDB|5K7F] (from Myxococcus xanthus, 24% identity) [pubmed|27940564]
• [AF|P32398]

Expression and Regulation

Operons

• genes: [gene|591C37CE3A583ADFC3006A8D1C9D07FA4F8F624C|yhgD]-[gene|8CA084B7BAA4969534DFEFBAFE31D25125354630|yhgE]

  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-B504 (yhgD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1503 NBRP B. subtilis, Japan]
• BKE10150 ([gene|591C37CE3A583ADFC3006A8D1C9D07FA4F8F624C|yhgD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10150 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTGTATTCACCTCGAAAC,  downstream forward: _UP4_TAGATAATCCTTTCTCTTTG
• BKK10150 ([gene|591C37CE3A583ADFC3006A8D1C9D07FA4F8F624C|yhgD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10150 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTGTATTCACCTCGAAAC,  downstream forward: _UP4_TAGATAATCCTTTCTCTTTG

References

Reviews

• 24006471

Research papers

• 27940564