nhaX

168

general stress protein, putative regulator of [protein|A7F1B4C0D32E18773170BFBEEB94E5EF55C7DB97|nhaC]

locus: BSU_09690

Molecular weight: 17.87 kDa

pI: 4.44

Protein length: 166 aa

Gene length: 501 bp

function: unknown

product: unknown

essential: no

synonyms: nhaX, yheK

List of homologs in different organisms, belongs to COG0589 (Galperin et al., 2021)

Gene

Coordinates: 1,044,373 → 1,044,873

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The protein

Protein family

• universal stress protein A family (with [protein|5A4CDE1CFE319E4471A15702ED1632C96270528D|yxiE], according to UniProt)

Structure

• [PDB|1WJG] (from Thermus thermophilus, 30% identity)
• [AF|O07552]

Expression and Regulation

Operons

• genes: [gene|D0BBFE1706429A98B7E93998794061A112FE8ECA|nhaX]

  description: [Pubmed|22383849]

  regulation

  • induced by stress ([protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]) [Pubmed|11544224]

  sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]

Biological materials

Mutant

• BKE09690 (Δ[gene|D0BBFE1706429A98B7E93998794061A112FE8ECA|nhaX]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE09690 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCTTCTCACCCTTTCAA,  downstream forward: _UP4_TGAGCACGCCCTGTGCTCAC
• BKK09690 (Δ[gene|D0BBFE1706429A98B7E93998794061A112FE8ECA|nhaX]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK09690 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCTTCTCACCCTTTCAA,  downstream forward: _UP4_TGAGCACGCCCTGTGCTCAC

References

• 11544224,11274110,23033921