yfhA

168

[wiki|ABC transporter] for the siderophore schizokinen and arthrobactin (permease), works with ATPase [protein|5C52DB31F378E49AABE5D937DD901A68F3810477|yusV]

locus: BSU_08460

Molecular weight: 35.80 kDa

pI: 10.26

Protein length: 343 aa

Gene length: 1032 bp

function: [wiki|acquisition of iron]

product: [wiki|ABC transporter] for the siderophore schizokinen and arthrobactin (permease)

essential: no

synonyms: yfhA

List of homologs in different organisms, belongs to COG0609 (Galperin et al., 2021)

Gene

Coordinates: 921,472  922,503

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The protein

Protein family

• [wiki|Binding-protein-dependent transport system permease family] (according to UniProt)
• [wiki|FecCD subfamily] (according to UniProt)

Structure

• [PDB|2NQ2] (complex with [protein|5C52DB31F378E49AABE5D937DD901A68F3810477|yusV]-like protein, from Haemophilus influenzae, 33% identity) [pubmed|17158291]
• [AF|O31569]

Paralogous protein(s)

• [protein|800EAB1D8617589CCAC68FB874EFCDE4C77962E1|fecE], [protein|EC98685EE0E3CE6CE8DC33409481AE96315279AC|fhuG]

[wiki|Localization]

• cell membrane [Pubmed|10092453]

Biological materials

Mutant

• MGNA-C313 (yfhA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2311 NBRP B. subtilis, Japan]
• BKE08460 ([gene|34A7E22B4EF118EF5A76F8CC2DABBB023BC9A2E9|yfhA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08460 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTTCATAGCTTCGCCCCCCT,  downstream forward: _UP4_TAATCGTTACACCCATTTTC
• BKK08460 ([gene|34A7E22B4EF118EF5A76F8CC2DABBB023BC9A2E9|yfhA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08460 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TTTCATAGCTTCGCCCCCCT,  downstream forward: _UP4_TAATCGTTACACCCATTTTC

References

• 36815589,10092453,16672620,12354229,17158291