murR

murR
168

transcriptional repressor of genes required for the utilization of N-acetylmuramic acid

locus
BSU_01690
Molecular weight
30.56 kDa
pI
6.87
Protein length
Gene length
function
regulation of muramic acid utilization
product
transcriptional repressor
essential
no
synonyms
murR, ybbH

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1737 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
191,183  192,034
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The protein
[wiki|Domains]
HTH rpiR-type domain (aa 3-79) (according to UniProt)
[wiki|SIS domain] (aa 123-264) (according to UniProt)
Structure
[PDB|2O3F] (N-terminal domain)
[AF|Q45581]
Expression and Regulation
Operons
genes
[gene|0B1F43F43A4DC1574A153DBFBAA5D0A1855F9B61|murQ]-[gene|125872506C400CB6B3DAEA8B5130B064DFBA4494|murR]-[gene|178D5E2AA1225FE909E6F2B63B3595F5ABB8E7A2|murP]-[gene|DEACFD435DB01C4B3ADEF397BEE08E2E7C7FCC36|amiE]-[gene|A5D4BF262BD365DCEBA9358C8DB295E605DE4D84|nagZ]-[gene|005D37F34CA3D6891F7D8FF7A2AFA1CBCB556FFE|namZ]
description
[Pubmed|22383849]
regulation
expressed in late exponential and early stationary phase [Pubmed|20400549]
regulatory mechanism
[protein|125872506C400CB6B3DAEA8B5130B064DFBA4494|murR]: repression, [pubmed|30038046], in [regulon|protein:125872506C400CB6B3DAEA8B5130B064DFBA4494|murR regulon]
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[gene|0B1F43F43A4DC1574A153DBFBAA5D0A1855F9B61|murQ]→[gene|005D37F34CA3D6891F7D8FF7A2AFA1CBCB556FFE|namZ]

2024-03-24 05:12:40

Jstuelk

90

63a61d46d8ccef554859655721937254bb90adc4

0CB715DED62C09573A88E4102ECFE473836124B4

Biological materials
Mutant
MGNA-B951 (ybbH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1950 NBRP B. subtilis, Japan]
BKE01690 ([gene|125872506C400CB6B3DAEA8B5130B064DFBA4494|murR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE01690 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TGTGGCCATTCTAGTTCTCT,  downstream forward: _UP4_TAAGGCATCTTGAAGGGGAG
BKK01690 ([gene|125872506C400CB6B3DAEA8B5130B064DFBA4494|murR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK01690 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TGTGGCCATTCTAGTTCTCT,  downstream forward: _UP4_TAAGGCATCTTGAAGGGGAG
References
15060041,20400549,10627040,22383849,30038046

125872506C400CB6B3DAEA8B5130B064DFBA4494

Page visits: 3727

Time of last update: 2024-03-28 20:10:59

Author of last update: Melvin.boenninger