azlD

168

amino acid exporter (with [protein|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC])

locus: BSU_26700

Molecular weight: 11.83 kDa

pI: 9.96

Protein length: 110 aa

Gene length: 333 bp

function: export of amino acids

product: component of amino acid exporter (with [protein|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC])

essential: no

synonyms: azlD, yrdI

List of homologs in different organisms, belongs to COG1687 (Galperin et al., 2021)

Gene

Coordinates: 2,728,647  2,728,979

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The protein

Catalyzed reaction/ biological activity

• export of some branched-chain amino acids, histidine, and asparagine as well as 2,3-diaminopropionic acid (in complex with [protein|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]) [pubmed|38470260,36377869,38193659]

Protein family

• AzlD/HI_1737/HP1330 family (single member, according to UniProt)

Structure

• [AF|O07923]

[wiki|Localization]

• cell membrane (according to Swiss-Prot)

Biological materials

Mutant

• GP3601 (Δ[gene|D7397591C2157EBB1951ED3DC1E315F9AE7A4BB3|azlB]-[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]-[gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]::''kan'') , available in [wiki|Jörg Stülke]'s lab [pubmed|36377869]
• GP3622 (Δ[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]-[gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]::''kan'') , available in [wiki|Jörg Stülke]'s lab [pubmed|36377869]
• GP3623 (Δ[gene|D7397591C2157EBB1951ED3DC1E315F9AE7A4BB3|azlB]-[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]-[gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]::''spec'') , available in [wiki|Jörg Stülke]'s lab [pubmed|36377869]
• BKE26700 ([gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE26700 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTGCTGCGTCATAGTCA,  downstream forward: _UP4_TAACCGATATCGGAAACGAT
• BKK26700 ([gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK26700 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTGCTGCGTCATAGTCA,  downstream forward: _UP4_TAACCGATATCGGAAACGAT

References

• 9287000,12081967,12879215,36377869,38193659,38470260