azlC

168

amino acid exporter (with [protein|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD])

locus: BSU_26710

Molecular weight: 28.22 kDa

pI: 9.73

Protein length: 254 aa

Gene length: 765 bp

function: export of amino acids

product: component of amino acid exporter (with [protein|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD])

essential: no

synonyms: azlC, yrdH

List of homologs in different organisms, belongs to COG1296 (Galperin et al., 2021)

Gene

Coordinates: 2,728,976 → 2,729,740

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The protein

Catalyzed reaction/ biological activity

• export of some branched-chain amino acids, histidine, and asparagine as well as 2,3-diaminopropionic acid (in complex with [protein|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]) [pubmed|38470260,36377869,38193659]

Protein family

• azlC family (single member, according to UniProt)

Structure

• [AF|O07942]

[wiki|Localization]

• cell membrane (according to Swiss-Prot)

Biological materials

Mutant

• GP3601 (Δ[gene|D7397591C2157EBB1951ED3DC1E315F9AE7A4BB3|azlB]-[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]-[gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]::''kan'') , available in [wiki|Jörg Stülke]'s lab [pubmed|36377869]
• GP3622 (Δ[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]-[gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]::''kan'') , available in [wiki|Jörg Stülke]'s lab [pubmed|36377869]
• GP3623 (Δ[gene|D7397591C2157EBB1951ED3DC1E315F9AE7A4BB3|azlB]-[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]-[gene|7A1445B7AFD9C3AA45EF67E51F5D233FCC5F8884|azlD]::''spec'') , available in [wiki|Jörg Stülke]'s lab [pubmed|36377869]
• BKE26710 (Δ[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE26710 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAATCAACAACCTCCTACA,  downstream forward: _UP4_GTATGACGATGACTATGACG
• BKK26710 (Δ[gene|C90D642197EE589F9D33CD5AA0B1069E3BC124A8|azlC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK26710 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAATCAACAACCTCCTACA,  downstream forward: _UP4_GTATGACGATGACTATGACG

References

• 9287000,12081967,12879215,36377869,38193659,38470260