Difference between revisions of "AtpB"

From SubtiWiki
Jump to: navigation, search
Line 1: Line 1:
* '''Description:''' ATP synthase (subunit a) <br/><br/>
+
* '''Description:''' [[ATP synthase]], part of the Fo complex (subunit a) <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 10: Line 10:
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || ATP synthase (subunit a))
+
|style="background:#ABCDEF;" align="center"| '''Product''' || [[ATP synthase]] (subunit a))
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || ATP synthesis  
+
|style="background:#ABCDEF;" align="center"|'''Function''' || [[ATP synthesis]]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36870 atpB]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36870 atpB]
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/AtpB AtpB]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 9.36   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 9.36   
Line 35: Line 37:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
 
 
 
<br/><br/>
 
<br/><br/>
  
Line 90: Line 88:
  
 
* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
 +
** [[AtpB|A]](1)-[[AtpF|B]](2)-[[AtpE|C]](12) - [[AtpA|alpha]](3)-[[AtpD|beta]](3)-[[AtpG|gamma]]-[[AtpH|delta]]-[[AtpC|epsilon]]
  
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot),  membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]  
+
* '''[[Localization]]:'''  
 +
** membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]  
  
 
=== Database entries ===
 
=== Database entries ===
  
* '''Structure:'''
+
* '''Structure:''' [http://www.rcsb.org/pdb/101/motm.do?momID=72&evtc=Suggest&evta=Moleculeof%20the%20Month&evtl=OtherOptions see here an overview on ATPase structure]
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P37813 P37813]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P37813 P37813]
Line 111: Line 111:
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=atpB_3786878_3787612_-1 atpB] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=atpB_3786878_3787612_-1 atpB] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 16:46, 11 August 2013

  • Description: ATP synthase, part of the Fo complex (subunit a)

Gene name atpB
Synonyms
Essential no
Product ATP synthase (subunit a))
Function ATP synthesis
Gene expression levels in SubtiExpress: atpB
Interactions involving this protein in SubtInteract: AtpB
MW, pI 26 kDa, 9.36
Gene length, protein length 732 bp, 244 aa
Immediate neighbours atpE, atpI
Sequences Protein DNA DNA_with_flanks
Genetic context
AtpB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AtpB expression.png















Categories containing this gene/protein

ATP synthesis, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU36870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP synthesis see a video
  • Protein family: ATPase A chain family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)

M Santana, M S Ionescu, A Vertes, R Longin, F Kunst, A Danchin, P Glaser
Bacillus subtilis F0F1 ATPase: DNA sequence of the atp operon and characterization of atp mutants.
J Bacteriol: 1994, 176(22);6802-11
[PubMed:7961438] [WorldCat.org] [DOI] (P p)