Difference between revisions of "AsnH"

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=== Database entries ===
 
=== Database entries ===

Revision as of 18:49, 16 July 2011

  • Description: asparagine synthase (glutamine-hydrolysing)

Gene name asnH
Synonyms yxaN
Essential no
Product asparagine synthase (glutamine-hydrolysing))
Function biosynthesis of asparagine
Metabolic function and regulation of this protein in SubtiPathways:
Asp, Asn
MW, pI 85 kDa, 5.528
Gene length, protein length 2241 bp, 747 aa
Immediate neighbours yxnB, yxaM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AsnH context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

AbrB regulon, CodY regulon

The gene

Basic information

  • Locus tag: BSU39920

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + L-aspartate + L-glutamine + H2O = AMP + diphosphate + L-asparagine + L-glutamate (according to Swiss-Prot)
  • Protein family: asparagine synthetase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • repressed during logrithmic growth (AbrB) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References