AseA

• Description: As(III) efflux pump
  
  

Gene name	aseA
Synonyms	ydfA
Essential	no
Product	As(III) efflux pump
Function	resistance to arsenite
Gene expression levels in SubtiExpress: aseA
Metabolic function and regulation of this protein in SubtiPathways: metal ion homeostasis
MW, pI	47 kDa, 8.968
Gene length, protein length	1305 bp, 435 aa
Immediate neighbours	aseR, ydzS/1
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, resistance against toxic metals

This gene is a member of the following regulons

AseR regulon

The gene

Basic information

• Locus tag: BSU05340

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): YwrK

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P96678

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: aseA PubMed

• Sigma factor:

• Regulation:
  • induced by As(III) (AseR) PubMed

• Regulatory mechanism:
  • AseR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Charles M Moore, Ahmed Gaballa, Monica Hui, Rick W Ye, John D Helmann
Genetic and physiological responses of Bacillus subtilis to metal ion stress.
Mol Microbiol: 2005, 57(1);27-40
[PubMed:15948947] [WorldCat.org] [DOI] (P p)