Difference between revisions of "AscR"

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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O35038 O35038]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O35038 O35038]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU29400]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU29400]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''

Revision as of 09:33, 25 June 2009

  • Description: transcriptional activator of the tcy operon

Gene name ytlI
Synonyms
Essential no
Product transcriptional activator (LysR type)
Function regulation of sulphur metabolism
MW, pI 35 kDa, 6.228
Gene length, protein length 924 bp, 308 aa
Immediate neighbours ytmI, ytkL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtlI context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU29400

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: ytlI
  • Regulation: repressed in the presence of cysteine (CymR) PubMed
    • repressed in the presence of cysteine (CymR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sergine Even, Pierre Burguière, Sandrine Auger, Olga Soutourina, Antoine Danchin, Isabelle Martin-Verstraete
Global control of cysteine metabolism by CymR in Bacillus subtilis.
J Bacteriol: 2006, 188(6);2184-97
[PubMed:16513748] [WorldCat.org] [DOI] (P p)

Pierre Burguière, Juliette Fert, Isabelle Guillouard, Sandrine Auger, Antoine Danchin, Isabelle Martin-Verstraete
Regulation of the Bacillus subtilis ytmI operon, involved in sulfur metabolism.
J Bacteriol: 2005, 187(17);6019-30
[PubMed:16109943] [WorldCat.org] [DOI] (P p)

Kyle N Erwin, Shunji Nakano, Peter Zuber
Sulfate-dependent repression of genes that function in organosulfur metabolism in Bacillus subtilis requires Spx.
J Bacteriol: 2005, 187(12);4042-9
[PubMed:15937167] [WorldCat.org] [DOI] (P p)

Jean-Yves Coppée, Sandrine Auger, Evelyne Turlin, Agnieszka Sekowska, Jean-Pierre Le Caer, Valérie Labas, Valérie Vagner, Antoine Danchin, Isabelle Martin-Verstraete
Sulfur-limitation-regulated proteins in Bacillus subtilis: a two-dimensional gel electrophoresis study.
Microbiology (Reading): 2001, 147(Pt 6);1631-1640
[PubMed:11390694] [WorldCat.org] [DOI] (P p)