ArtR

• Description: high affinity arginine ABC transporter (ATP-binding protein)
  
  

Gene name	artR
Synonyms	yqiZ
Essential	no
Product	high affinity arginine ABC transporter (ATP-binding protein)
Function	arginine uptake
Gene expression levels in SubtiExpress: artR
Interactions involving this protein in SubtInteract: ArtR
Metabolic function and regulation of this protein in SubtiPathways: artR
MW, pI	26 kDa, 9.131
Gene length, protein length	720 bp, 240 aa
Immediate neighbours	yqjA, artQ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, membrane proteins

The gene

Basic information

• Locus tag: BSU23960

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: ArtR-ArtQ-ArtP PubMed

• Localization: attached to the membrane via ArtQ PubMed

Database entries

• Structure: 2Q0H (in complex with ADP-Mg2+, Geobacillus stearothermophilus, 63% identity)

• Swiss prot entry: P54537

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: artP-artQ-artR PubMed

• Expression browser: artR PubMed

• Sigma factor:

• Regulation:
  • repressed by casamino acids PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147] [WorldCat.org] [DOI] (P p)

A Sekowska, S Robin, J J Daudin, A Hénaut, A Danchin
Extracting biological information from DNA arrays: an unexpected link between arginine and methionine metabolism in Bacillus subtilis.
Genome Biol: 2001, 2(6);RESEARCH0019
[PubMed:11423008] [WorldCat.org] [DOI] (I p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)