Difference between revisions of "ArtP"

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(References)
(Extended information on the protein)
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
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** K(D) for Arg: 43 nM {{PubMed|23038252}}
 +
** K(D) for Lys: 657 myM {{PubMed|23038252}}
  
 
* '''Domains:'''  
 
* '''Domains:'''  

Revision as of 18:34, 8 October 2012

  • Description: high affinity arginine ABC transporter (ATP-binding protein)

Gene name artP
Synonyms yqiX
Essential no
Product high affinity arginine ABC transporter (ATP-binding protein)
Function arginine uptake
Gene expression levels in SubtiExpress: artP
Interactions involving this protein in SubtInteract: ArtP
Metabolic function and regulation of this protein in SubtiPathways:
Ammonium/ glutamate
MW, pI 28 kDa, 5.086
Gene length, protein length 765 bp, 255 aa
Immediate neighbours artQ, yqiW
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YqiX context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ArtP expression.png



















Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU23980

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacterial solute-binding protein 3 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2Q2C (Geobacillus stearothermophilus)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

George D Glekas, Brendan J Mulhern, Abigail Kroc, Keegan A Duelfer, Victor Lei, Christopher V Rao, George W Ordal
The Bacillus subtilis chemoreceptor McpC senses multiple ligands using two discrete mechanisms.
J Biol Chem: 2012, 287(47);39412-8
[PubMed:23038252] [WorldCat.org] [DOI] (I p)

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)

Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147] [WorldCat.org] [DOI] (P p)

A Sekowska, S Robin, J J Daudin, A Hénaut, A Danchin
Extracting biological information from DNA arrays: an unexpected link between arginine and methionine metabolism in Bacillus subtilis.
Genome Biol: 2001, 2(6);RESEARCH0019
[PubMed:11423008] [WorldCat.org] [DOI] (I p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)