Difference between revisions of "AroC"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of aromatic amino acids | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of aromatic amino acids | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23080 aroC] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/phenyl_tyr_tryp.html Phe, Tyr, Trp]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/phenyl_tyr_tryp.html Phe, Tyr, Trp]''' | ||
| Line 24: | Line 24: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[serA]]'', ''[[rsiX]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[serA]]'', ''[[rsiX]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU23080 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU23080 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU23080 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:aroC_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:aroC_context.gif]] | ||
Revision as of 14:10, 13 May 2013
- Description: 3-dehydroquinate dehydratase
| Gene name | aroC |
| Synonyms | |
| Essential | no |
| Product | 3-dehydroquinate dehydratase |
| Function | biosynthesis of aromatic amino acids |
| Gene expression levels in SubtiExpress: aroC | |
| Metabolic function and regulation of this protein in SubtiPathways: Phe, Tyr, Trp | |
| MW, pI | 27 kDa, 4.898 |
| Gene length, protein length | 765 bp, 255 aa |
| Immediate neighbours | serA, rsiX |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23080
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 3-dehydroquinate = 3-dehydroshikimate + H2O (according to Swiss-Prot)
- Protein family: type-I 3-dehydroquinase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P35146
- KEGG entry: [3]
- E.C. number: 4.2.1.10
Additional information
Expression and regulation
- Operon: aroC PubMed
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
V Azevedo, A Sorokin, S D Ehrlich, P Serror
The transcriptional organization of the Bacillus subtilis 168 chromosome region between the spoVAF and serA genetic loci.
Mol Microbiol: 1993, 10(2);397-405
[PubMed:7934830]
[WorldCat.org]
[DOI]
(P p)
R J Warburg, I Mahler, D J Tipper, H O Halvorson
Cloning the Bacillus subtilis 168 aroC gene encoding dehydroquinase.
Gene: 1984, 32(1-2);57-66
[PubMed:6442253]
[WorldCat.org]
[DOI]
(P p)
