Difference between revisions of "ArgD"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU11220
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P36839 P36839]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P36839 P36839]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU11220 BSU11220]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU11220]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.6.1.11 2.6.1.11]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.6.1.11 2.6.1.11]

Revision as of 11:20, 3 June 2009

  • Description: acetylornithine transaminase

Gene name argD
Synonyms
Essential no
Product acetylornithine transaminase
Function biosynthesis of arginine
MW, pI 40 kDa, 5.929
Gene length, protein length 1155 bp, 385 aa
Immediate neighbours argB, carA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ArgD context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU11220

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate (according to Swiss-Prot)
  • Protein family: ArgD subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: repressed by casamino acids PubMed, repressed by arginine (AhrC)
  • Regulatory mechanism: AhrC: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Mäder et al. (2002) Transcriptome and Proteome Analysis of Bacillus subtilis Gene Expression Modulated by Amino Acid Availability. J. Bacteriol 184: 1844288-4295 PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed