Difference between revisions of "ArgC"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU11190
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P23715 P23715]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P23715 P23715]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU11190 BSU11190]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU11190]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.2.1.38 1.2.1.38]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.2.1.38 1.2.1.38]

Revision as of 09:13, 3 June 2009

  • Description: N-acetyl-g-glutamyl-phosphate reductase

Gene name argC
Synonyms
Essential no
Product N-acetyl-g-glutamyl-phosphate reductase
Function biosynthesis of arginine
MW, pI 37 kDa, 5.167
Gene length, protein length 1038 bp, 346 aa
Immediate neighbours yitZ, argJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ArgC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU11190

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH (according to Swiss-Prot)
  • Protein family: Type 1 subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: repressed by casamino acids PubMed, repressed by arginine (AhrC)
  • Regulatory mechanism: AhrC: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Mäder et al. (2002) Transcriptome and Proteome Analysis of Bacillus subtilis Gene Expression Modulated by Amino Acid Availability. J. Bacteriol 184: 1844288-4295 PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed