AprX

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  • Description: intracellular alkaline serine protease

Gene name aprX
Synonyms
Essential no
Product intracellular alkaline serine protease
Function protein degradation
Gene expression levels in SubtiExpress: aprX
MW, pI 47 kDa, 4.974
Gene length, protein length 1326 bp, 442 aa
Immediate neighbours ymaE, ymzE/1
Sequences Protein DNA Advanced_DNA
Genetic context
AprX context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AprX expression.png
























Categories containing this gene/protein

utilization of nitrogen sources other than amino acids

This gene is a member of the following regulons

LexA regulon

The gene

Basic information

  • Locus tag: BSU17260

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: aprX (according to [DBTBS])
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Alessandra Albertini, University of Pavia, Italy homepage

Your additional remarks

References

Nora Au, Elke Kuester-Schoeck, Veena Mandava, Laura E Bothwell, Susan P Canny, Karen Chachu, Sierra A Colavito, Shakierah N Fuller, Eli S Groban, Laura A Hensley, Theresa C O'Brien, Amish Shah, Jessica T Tierney, Louise L Tomm, Thomas M O'Gara, Alexi I Goranov, Alan D Grossman, Charles M Lovett
Genetic composition of the Bacillus subtilis SOS system.
J Bacteriol: 2005, 187(22);7655-66
[PubMed:16267290] [WorldCat.org] [DOI] (P p)

Angela Valbuzzi, Eugenio Ferrari, Alessandra M Albertini
A novel member of the subtilisin-like protease family from Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 11);3121-3127
[PubMed:10589719] [WorldCat.org] [DOI] (P p)