AppC

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Gene name appC
Synonyms
Essential no
Product oligopeptide ABC transporter (permease))
Function uptake of oligopeptides
Interactions involving this protein in SubtInteract: AppC
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 33 kDa, 9.777
Gene length, protein length 909 bp, 303 aa
Immediate neighbours appB, yjbA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AppC context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

ABC transporters, utilization of nitrogen sources other than amino acids, membrane proteins

This gene is a member of the following regulons

CodY regulon, ScoC regulon

The gene

Basic information

  • Locus tag: BSU11400

Expression

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ABC transmembrane type-1 domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • repressed during exponential growth (ScoC) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References