AlsR

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  • Description: transcriptional activator of the alsSD operon

Gene name alsR
Synonyms
Essential
Product transcriptional activator(LysR family)
Function regulation of acetoin synthesis (alsSD)
MW, pI 34 kDa, 7.288
Gene length, protein length 906 bp, 302 aa
Immediate neighbours
Gene sequence (+200bp) Protein sequence
Genetic context
AlsR context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

no acetoin production

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds the promoter region of the alsS-alsD operon in the presence of acetate, activates transcription
  • Protein family: LysR family of transcription factors
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Elisabeth Härtig, Braunschweig, Germany

Your additional remarks

References

  1. Renna, M. C., Najimudin, N., Winik, L. R., and Zahler, S. A. (1993). Regulation of the Bacillus subtilis alsS, alsD, and alsR genes involved in post-exponential-phase production of acetoin. J. Bacteriol. 175, 3863-3875. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed