AlsR

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  • Description: transcriptional activator of the alsS-alsD operon<br/><br/>
Gene name alsR
Synonyms
Essential no
Product transcriptional activator(LysR family)
Function regulation of acetoin synthesis (alsS-alsD)
Metabolic function and regulation of this protein in SubtiPathways: <br/>Central C-metabolism
MW, pI 34 kDa, 7.288
Gene length, protein length 906 bp, 302 aa
Immediate neighbours alsS, ywrK
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> AlsR context.gif
<div align="right"> <small>This image was kindly provided by SubtiList</small></div>

<br/><br/><br/><br/><br/><br/>

The gene

Basic information

  • Locus tag: BSU36020

Phenotypes of a mutant

no acetoin production

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds the promoter region of the alsS-alsD operon in the presence of acetate, activates transcription
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: AMBs3 (spc), available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Elisabeth Härtig, Braunschweig, Germany Homepage

Your additional remarks

References

<pubmed>7685336, </pubmed>