AlsR

From SubtiWiki
Revision as of 14:52, 20 July 2009 by Lflorez (talk | contribs)
Jump to: navigation, search
  • Description: transcriptional activator of the alsSD operon

Gene name alsR
Synonyms
Essential no
Product transcriptional activator(LysR family)
Function regulation of acetoin synthesis (alsSD)
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 34 kDa, 7.288
Gene length, protein length 906 bp, 302 aa
Immediate neighbours alsS, ywrK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AlsR context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU36020

Phenotypes of a mutant

no acetoin production

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds the promoter region of the alsS-alsD operon in the presence of acetate, activates transcription
  • Protein family: LysR family of transcription factors
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Elisabeth Härtig, Braunschweig, Germany Homepage

Your additional remarks

References

M C Renna, N Najimudin, L R Winik, S A Zahler
Regulation of the Bacillus subtilis alsS, alsD, and alsR genes involved in post-exponential-phase production of acetoin.
J Bacteriol: 1993, 175(12);3863-75
[PubMed:7685336] [WorldCat.org] [DOI] (P p)