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| − | * '''Description:''' L-alanine dehydrogenase <br/><br/>
| + | NDH8wq <a href="http://irfsjefqmfjq.com/">irfsjefqmfjq</a>, [url=http://jgenqmspgcar.com/]jgenqmspgcar[/url], [link=http://anrcnpxqlycn.com/]anrcnpxqlycn[/link], http://ijiqzxcextso.com/ |
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| − | {| align="right" border="1" cellpadding="2"
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| − | |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| − | |''ald''
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| − | |-
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| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''spoVN ''
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| − | |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || L-alanine dehydrogenase
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| − | |-
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || alanine utilization
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/ala_gly_ser.html Ala, Gly, Ser]'''
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| − | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 39 kDa, 5.125
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| − | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1134 bp, 378 aa
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| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yukF]]'', ''[[yukJ]]''
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| − | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15181]+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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| − | |colspan="2" | '''Genetic context''' <br/> [[Image:ald_context.gif]]
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| − | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| − | |}
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| − | | |
| − | __TOC__
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| − | <br/><br/><br/><br/><br/><br/>
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| − | | |
| − | = [[Categories]] containing this gene/protein =
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| − | {{SubtiWiki category|[[utilization of amino acids]]}}
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| − | | |
| − | = This gene is a member of the following [[regulons]] =
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| − | | |
| − | | |
| − | =The gene=
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| − | | |
| − | === Basic information ===
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| − | * '''Locus tag:''' BSU31930
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| − | | |
| − | ===Phenotypes of a mutant ===
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| − | | |
| − | === Database entries ===
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| − | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ald.html]
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| − | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10468]
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| − | | |
| − | === Additional information===
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| − | | |
| − | | |
| − | =The protein=
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| − | | |
| − | === Basic information/ Evolution ===
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| − | * '''Catalyzed reaction/ biological activity:''' L-alanine + H<sub>2</sub>O + NAD<sup>+</sup> = pyruvate + NH<sub>3</sub> + NADH (according to Swiss-Prot)
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| − | * '''Protein family:''' AlaDH/PNT family (according to Swiss-Prot)
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| − | * '''Paralogous protein(s):'''
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| − | | |
| − | === Extended information on the protein ===
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| − | * '''Kinetic information:'''
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| − | * '''Domains:'''
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| − | * '''Modification:'''
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| − | * '''Cofactor(s):'''
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| − | * '''Effectors of protein activity:'''
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| − | * '''[[SubtInteract|Interactions]]:'''
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| − | * '''[[Localization]]:''' cytoplasm (according to Swiss-Prot)
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| − | | |
| − | === Database entries ===
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| − | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2EEZ 2EEZ] (from ''Thermus thermophilus hb8 mutant'', 55% identity, 66% similarity)
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| − | * '''UniProt:''' [http://www.uniprot.org/uniprot/Q08352 Q08352]
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| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU31930]
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| − | * '''E.C. number:''' [http://www.expasy.org/enzyme/1.4.1.1 1.4.1.1]
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| − | | |
| − | === Additional information===
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| − | =Expression and regulation=
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| − | * '''Operon:''' ''[[ald]]'' {{PubMed|8226620}}
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| − | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8226620}}
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| − | * '''Regulation:'''
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| − | ** induced by alanine {{PubMed|8226620}}
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| − | * '''Regulatory mechanism:'''
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| − | * '''Additional information:'''
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| − | | |
| − | =Biological materials =
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| − | * '''Mutant:'''
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| − | * '''Expression vector:'''
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| − |
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| − | * '''lacZ fusion:'''
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| − | * '''GFP fusion:'''
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| − | * '''two-hybrid system:'''
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| − | * '''Antibody:'''
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| − | =Labs working on this gene/protein=
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| − | =Your additional remarks=
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| − | =References=
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| − | <pubmed>19114526,9168598,17183219,8226620,, </pubmed>
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| − | [[Category:Protein-coding genes]]
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