Difference between revisions of "Adk"

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* '''Additional information:'''
 
* '''Additional information:'''
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** number of protein molecules per cell (minimal medium with glucose and ammonium): 2183 {{PubMed|24696501}}
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** number of protein molecules per cell (complex medium with amino acids, without glucose): 11614 {{PubMed|24696501}}
  
 
=Biological materials =
 
=Biological materials =

Revision as of 09:52, 17 April 2014

  • Description: adenylate kinase

Gene name adk
Synonyms
Essential yes PubMed
Product adenylate kinase
Function ADP formation
Gene expression levels in SubtiExpress: adk
Metabolic function and regulation of this protein in SubtiPathways:
adk
MW, pI 23 kDa, 4.449
Gene length, protein length 651 bp, 217 aa
Immediate neighbours secY, map
Sequences Protein DNA DNA_with_flanks
Genetic context
Adk context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Adk expression.png




























Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides, essential genes

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU01370

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + AMP = 2 ADP (according to Swiss-Prot)
  • Protein family: adenylate kinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 2183 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 11614 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References