AdeC

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  • Description: adenine deaminase

Gene name adeC
Synonyms ade, yzaD
Essential no
Product adenine deaminase
Function utilization of adenine as nitrogen source,
purine salvage and interconversion
Metabolic function and regulation of this protein in SubtiPathways:
Purine salvage, Purine catabolism
MW, pI 62 kDa, 4.724
Gene length, protein length 1731 bp, 577 aa
Immediate neighbours ktrC, rnjA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AdeC context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU14520

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Adenine + H2O = hypoxanthine + NH3 (according to Swiss-Prot)
  • Protein family: adenine deaminase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

P Nygaard, P Duckert, H H Saxild
Role of adenine deaminase in purine salvage and nitrogen metabolism and characterization of the ade gene in Bacillus subtilis.
J Bacteriol: 1996, 178(3);846-53
[PubMed:8550522] [WorldCat.org] [DOI] (P p)