acpA

168

acyl carrier protein

locus: BSU_15920

Molecular weight: 8.45 kDa

pI: 3.59

Protein length: 77 aa

Gene length: 234 bp

function: fatty acid biosynthesis

product: acyl carrier protein

essential: yes

ec: null

synonyms: acpA, acpP

List of homologs in different organisms, belongs to COG0236 (Galperin et al., 2021)

Gene

Coordinates: 1,665,337  1,665,570

Phenotypes of a mutant

• essential [Pubmed|12682299]

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The protein

Protein family

• acyl carrier protein (ACP) family (single member, according to UniProt)

[wiki|Domains]

• [wiki|Carrier domain] (aa 2-77) (according to UniProt)

Structure

• [PDB|1F80] (complex with [protein|200BE4802FCE3C860565B374EAADC9C1FEEF3E49|acpS]) [Pubmed|10997907],  [PDB|3EJE] (complex with [protein|8FBC9A1AC108DC99E275D7A27C18C797D3CDB936|bioI]) [Pubmed|18838690],  [PDB|1HY8]
• [AF|P80643]

[wiki|Localization]

• cytoplasm (according to Swiss-Prot), during sporulation in the mother cell [Pubmed|19850612]

Biological materials

Expression vectors

• pGP2893: expression of Strep-''acpA'' by [wiki|pGP380] in ''B. subtilis'' suitable for [wiki|SPINE], available in [wiki|Jörg Stülke]'s lab

labs

• [wiki|Diego de Mendoza], Universidad Nacional de Rosario, Argentine [http://www.ibr.gov.ar/eng/investigacion/demendoza.htm homepage]

References

Reviews

• 15952903,20658980

Original Publications

• 36815589,10997907,19850612,12737802,18838690,20201588,23033921,33782055