Difference between revisions of "AcdA"

From SubtiWiki
Jump to: navigation, search
Line 31: Line 31:
 
__TOC__
 
__TOC__
  
<br/><br/>
+
<br/><br/><br/><br/><br/><br/>
  
 
=The gene=
 
=The gene=

Revision as of 15:06, 16 February 2010

  • Description: acyl-CoA dehydrogenase

Gene name acdA
Synonyms
Essential no
Product acyl-CoA dehydrogenase
Function fatty acid degradation
Metabolic function and regulation of this protein in SubtiPathways:
Fatty acid degradation
MW, pI 41 kDa, 4.951
Gene length, protein length 1137 bp, 379 aa
Immediate neighbours rpoE, fadF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AcdA context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU37170

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF (according to Swiss-Prot)
  • Protein family: acyl-CoA dehydrogenase family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 2Z1Q (from Thermus thermophilus hb8, 40% identity, 55% similarity)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the absence of long-chain fatty acids (FadR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References