Difference between revisions of "Aag"

From SubtiWiki
Jump to: navigation, search
(New page: * '''Description:''' write here <br/><br/> {| align="right" border="1" cellpadding="2" |- |style="background:#ABCDEF;" align="center"|'''Gene name''' |''yxlJ'' |- |style="background:#ABC...)
 
Line 1: Line 1:
* '''Description:''' write here <br/><br/>
+
* '''Description:''' 3-methyladenine DNA glycosylase <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yxlJ''
+
|''aag''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yxlJ ''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' ||  
+
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' ||  
+
|style="background:#ABCDEF;" align="center"| '''Product''' || 3-methyladenine DNA glycosylase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+
|style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 21 kDa, 6.117   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 21 kDa, 6.117   
Line 52: Line 52:
 
=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' removes hypoxanthine, 3-alkylated purines, and 1,N6-ethenoadenine from DNA; hypoxanthine and 1,N6-ethenoadenine are the preferred substrates
  
* '''Protein family:'''
+
* '''Protein family:''' AAG family of 3-methyladenine DNA glycosylases
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
Line 118: Line 118:
 
=References=
 
=References=
  
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
+
# Aamodt et al. (2004) The ''Bacillus subtilis'' counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N6-ethenoadenine as preferred substrates. ''J. Biol. Chem.'' '''279:''' 13601-13606-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/14729667 PubMed]

Revision as of 13:59, 13 February 2009

  • Description: 3-methyladenine DNA glycosylase

Gene name aag
Synonyms yxlJ
Essential no
Product 3-methyladenine DNA glycosylase
Function DNA repair
MW, pI 21 kDa, 6.117
Gene length, protein length 588 bp, 196 aa
Immediate neighbours
Gene sequence (+200bp) Protein sequence
Genetic context
YxlJ context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: removes hypoxanthine, 3-alkylated purines, and 1,N6-ethenoadenine from DNA; hypoxanthine and 1,N6-ethenoadenine are the preferred substrates
  • Protein family: AAG family of 3-methyladenine DNA glycosylases
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Aamodt et al. (2004) The Bacillus subtilis counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N6-ethenoadenine as preferred substrates. J. Biol. Chem. 279: 13601-13606-page. PubMed