ABC transporters

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transport proteins


Importers

Uptake of carbon sources

ATPase subunit of multiple sugar transport systems

Uptake of amino acids

Uptake of peptides

Uptake of compatible solutes for osmoprotection

Uptake of iron/ siderophores

Uptake of ions

Uptake of cofactors

ABC transporters of unknown function

Exporters

Efflux of antibiotics

  • VmlR: efflux of virginiamycin M and lincomycin
  • BmrA: efflux of multiple antibiotics
  • YheH-YheI: efflux of multiple antibiotics

Export of antibiotic substances

Export of toxic peptides

Export of cell wall components

Export of ions

Exporters of unknown function

Regulatory ABC transporters

  • CydC-CydD: required for expression of cytochrome bd
  • EcsA-EcsB: regulation of the secretion apparatus and of intra-membrane proteolysis
  • FtsE-FtsX: activation of Spo0A and initiation of sporulation
  • YheH-YheI: involved in the signalling pathway to activate KinA at the onset of sporulation
  • SufC: required for the synthesis of Fe-S clusters
  • YydI-(YydJ-YydH): control of LiaR-LiaS activity

Relevant publications