TreR

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  • Description: transcription repressor of the treP-treA-treR operon

Gene name treR
Synonyms yfxA
Essential no
Product transcription repressor
Function regulaation of trehalose utilization
MW, pI 27 kDa, 6.82
Gene length, protein length 714 bp, 238 aa
Immediate neighbours treA, yfkO
Gene sequence (+200bp) Protein sequence
Genetic context
TreR context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149
  2. Schöck F, Dahl MK (1996) Expression of the tre operon of Bacillus subtilis 168 is regulated by the repressor TreR. J Bacteriol. Aug;178(15): 4576-81. PubMed