ScpB
- Description: part of the condensin complex, chromosomal origin condensation and segregation
Gene name | scpB |
Synonyms | ypuH |
Essential | yes PubMed |
Product | DNA segregation and condensation protein |
Function | segregation of replication origins |
Gene expression levels in SubtiExpress: scpB | |
Interactions involving this protein in SubtInteract: ScpB | |
MW, pI | 21 kDa, 4.25 |
Gene length, protein length | 591 bp, 197 aa |
Immediate neighbours | ypuI, scpA |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
DNA condensation/ segregation, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23210
Phenotypes of a mutant
- essential PubMed
- scpB mutants are not viable on complex medim that allow rapid growth, but they are viable under conditions of slow growth PubMed
Database entries
- BsubCyc: BSU23210
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: scpB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- BsubCyc: BSU23210
- UniProt: P35155
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Sophie Nolivos, David Sherratt
The bacterial chromosome: architecture and action of bacterial SMC and SMC-like complexes.
FEMS Microbiol Rev: 2014, 38(3);380-92
[PubMed:24118085]
[WorldCat.org]
[DOI]
(I p)
Rodrigo Reyes-Lamothe, Emilien Nicolas, David J Sherratt
Chromosome replication and segregation in bacteria.
Annu Rev Genet: 2012, 46;121-43
[PubMed:22934648]
[WorldCat.org]
[DOI]
(I p)
Justin S Lenhart, Jeremy W Schroeder, Brian W Walsh, Lyle A Simmons
DNA repair and genome maintenance in Bacillus subtilis.
Microbiol Mol Biol Rev: 2012, 76(3);530-64
[PubMed:22933559]
[WorldCat.org]
[DOI]
(I p)
Original publications