QoxB

• Description: cytochrome aa3 quinol oxidase (subunit I)
  
  

Gene name	qoxB
Synonyms	ipa-38d
Essential	no
Product	cytochrome aa3 quinol oxidase (subunit I)
Function	respiration
Gene expression levels in SubtiExpress: qoxB
MW, pI	73 kDa, 8.848
Gene length, protein length	1947 bp, 649 aa
Immediate neighbours	qoxC, qoxA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

respiration, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU38160

Phenotypes of a mutant

• inactivation of qoxB restores beta-lactam resistance in a sigM mutant PubMed

Database entries

• BsubCyc: BSU38160

• DBTBS entry: no entry

• SubtiList entry: [1]

Additional information

• A mutation was found in this gene after evolution under relexed selection for sporulation PubMed

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Ubiquinol-8 + O₂ = Ubiquinone-8 + H₂O (according to Swiss-Prot)

• Protein family: heme-copper respiratory oxidase family (according to Swiss-Prot)

• Paralogous protein(s): CtaD

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): Cu(B) PubMed

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane PubMed

Database entries

• BsubCyc: BSU38160

• Structure:

• UniProt: P34956

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: qoxA-qoxB-qoxC-qoxD PubMed

• Expression browser: qoxB PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 89 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 1475 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: