ComK
Revision as of 09:57, 17 April 2014 by 134.76.70.252 (talk)
- Description: competence transcription factor (CTF)
Gene name | comK |
Synonyms | |
Essential | no |
Product | competence transcription factor (CTF) |
Function | regulation of competence and DNA uptake |
Gene expression levels in SubtiExpress: comK | |
Interactions involving this protein in SubtInteract: ComK | |
Metabolic function and regulation of this protein in SubtiPathways: comK | |
MW, pI | 22 kDa, 7.669 |
Gene length, protein length | 576 bp, 192 aa |
Immediate neighbours | yhzC, yhxD |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
genetic competence, transcription factors and their control, phosphoproteins
This gene is a member of the following regulons
AbrB regulon, CodY regulon, ComK regulon, DegU regulon, Rok regulon, Spo0A regulon
The ComK regulon
The gene
Basic information
- Locus tag: BSU10420
Phenotypes of a mutant
- no expression of competence genes, loss of genetic competence PubMed
Database entries
- BsubCyc: BSU10420
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- phosphorylated on Arg-65, Arg-157, Arg-161, Arg-165, Arg-186, and Arg-191 PubMed
- Effectors of protein activity:
Database entries
- BsubCyc: BSU10420
- Structure:
- UniProt: P40396
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: comK PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector: for expression, purification in E. coli with N-terminal His-tag, pRSETA available in Gerth lab
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Oscar Kuipers, University of Groningen, The Netherlands Homepage
Your additional remarks
References
Reviews
The ComK regulon
Original Publications