YhcS

• Description: sortase
  
  

Gene name	yhcS
Synonyms
Essential	no
Product	sortase
Function	anchoring of proteins to the cell wall
Gene expression levels in SubtiExpress: yhcS
Interactions involving this protein in SubtInteract: YhcS
MW, pI	21 kDa, 7.169
Gene length, protein length	594 bp, 198 aa
Immediate neighbours	yhcR, yhcT
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein secretion, membrane proteins

The gene

Basic information

• Locus tag: BSU09200

Database entries

• BsubCyc: BSU09200

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: C-terminal anchoring of proteins to the cell wall

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YhcS-YhcR PubMed, YhcS-YfkN PubMed (substrates of YhcS)

• Localization: membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU09200

• Structure:

• UniProt: P54603

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yhcS PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Thomas Spirig, Ethan M Weiner, Robert T Clubb
Sortase enzymes in Gram-positive bacteria.
Mol Microbiol: 2011, 82(5);1044-59
[PubMed:22026821] [WorldCat.org] [DOI] (I p)

Original publications

Additional referencecs: PubMed

Hamidreza Fasehee, Helga Westers, Albert Bolhuis, Haike Antelmann, Michael Hecker, Wim J Quax, Agha F Mirlohi, Jan Maareten van Dijl, Gholamreza Ahmadian
Functional analysis of the sortase YhcS in Bacillus subtilis.
Proteomics: 2011, 11(19);3905-13
[PubMed:21800427] [WorldCat.org] [DOI] (I p)