IolB

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  • Description: formation of 2-deoxy-5-keto-gluconic acid (4th reaction)

Gene name iolB
Synonyms yxdB
Essential no
Product formation of 2-deoxy-5-keto-gluconic acid (4th reaction)
Function myo-inositol catabolism
Gene expression levels in SubtiExpress: iolB
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 30 kDa, 4.77
Gene length, protein length 813 bp, 271 aa
Immediate neighbours iolC, iolA
Sequences Protein DNA DNA_with_flanks
Genetic context
IolB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
IolB expression.png




























Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

CcpA regulon, IolR regulon

The gene

Basic information

  • Locus tag: BSU39750

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 5-deoxy-glucuronic acid = 5-dehydro-2-deoxy-D-gluconic acid (according to Swiss-Prot)
  • Protein family: isomerase iolB family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2QJV (from Salmonella typhimurium, 49% identity, 65% similarity)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References