NhaK

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  • Description: cation/H+ antiporter

Gene name nhaK
Synonyms yvgP
Essential no
Product cation/H+ antiporter
Function monovalent cation export
Gene expression levels in SubtiExpress: nhaK
MW, pI 75 kDa, 9.222
Gene length, protein length 2010 bp, 670 aa
Immediate neighbours yvgO, cysJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YvgP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NhaK expression.png
























Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU33420

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: export of Na(+), K(+), Li(+), Rb(+)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: constitutive, expression increases in the presence of Na(+) and K(+) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Makoto Fujisawa, Ayumi Kusumoto, Yuko Wada, Takahiro Tsuchiya, Masahiro Ito
NhaK, a novel monovalent cation/H+ antiporter of Bacillus subtilis.
Arch Microbiol: 2005, 183(6);411-20
[PubMed:16021482] [WorldCat.org] [DOI] (P p)