YonT

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  • Description: toxin

Gene name yonT
Synonyms
Essential no
Product toxin
Function unknown
Gene expression levels in SubtiExpress: yonT
MW, pI 6 kDa, 12.857
Gene length, protein length 174 bp, 58 aa
Immediate neighbours as-yonT, yonS
Sequences Protein DNA DNA_with_flanks
Genetic context
YonT context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YonT expression.png















Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, SP-beta prophage

This gene is a member of the following regulons

as-yonT regulon

The gene

Basic information

  • Locus tag: BSU21000

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: panD family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information:
    • next to txpA, the yonT mRNA has the strongest Shine-Dalgarno region in B. subtilis PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Fabian M Commichau, Jörg Stülke
A mystery unraveled: essentiality of RNase III in Bacillus subtilis is caused by resident prophages.
PLoS Genet: 2012, 8(12);e1003199
[PubMed:23300472] [WorldCat.org] [DOI] (I p)

Original publications

Durand S, Gilet L, Condon C  
The essential function of B. subtilis RNase III is to silence foreign toxin genes. 
PLoS Genet. 2012 8(12): e1003181.
PubMed:23300471