YqgP

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  • Description: intramembrane protease

Gene name yqgP
Synonyms glpG, gluP
Essential no
Product intramembrane protease
Function cell division or sugar metabolism
Gene expression levels in SubtiExpress: yqgP
MW, pI 56 kDa, 5.507
Gene length, protein length 1521 bp, 507 aa
Immediate neighbours yqgQ, yqgO
Sequences Protein DNA Advanced_DNA
Genetic context
YqgP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqgP expression.png















Categories containing this gene/protein

proteolysis, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU24870

Phenotypes of a mutant

filamentous phenotype PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains (according to Swiss-Prot)
  • Protein family: peptidase S54 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Philip Rather
Role of rhomboid proteases in bacteria.
Biochim Biophys Acta: 2013, 1828(12);2849-54
[PubMed:23518036] [WorldCat.org] [DOI] (P p)

Original publications