DppE

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Gene name dppE
Synonyms dciAE
Essential no
Product dipeptide ABC transporter (dipeptide-binding protein)
Function uptake of dipeptides
Gene expression levels in SubtiExpress: dppE
Interactions involving this protein in SubtInteract: DppE
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 62 kDa, 5.523
Gene length, protein length 1647 bp, 549 aa
Immediate neighbours dppD, ykfA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DppE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DppE expression.png


























Categories containing this gene/protein

ABC transporters, utilization of nitrogen sources other than amino acids, membrane proteins

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

  • Locus tag: BSU12960

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacterial solute-binding protein 5 family (according to Swiss-Prot)
  • Paralogous protein(s): OppA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: GP1110 (spc), available in Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References