YloI

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  • Description: Coenzyme A biosynthesis bifunctional protein CoaBC; putative phosphopantothenoylcysteine synthetase/decarboxylase

Gene name yloI
Synonyms coaBC
Essential no
Product putative phosphopantothenoylcysteine synthetase/decarboxylase
Function biosynthesis of coenzyme A
Gene expression levels in SubtiExpress: yloI
Metabolic function and regulation of this protein in SubtiPathways:
Coenzyme A
MW, pI 43 kDa, 6.013
Gene length, protein length 1218 bp, 406 aa
Immediate neighbours yloH, priA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YloI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YloI expression.png




























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15700

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Germán Plata, Tobias Fuhrer, Tzu-Lin Hsiao, Uwe Sauer, Dennis Vitkup
Global probabilistic annotation of metabolic networks enables enzyme discovery.
Nat Chem Biol: 2012, 8(10);848-54
[PubMed:22960854] [WorldCat.org] [DOI] (I p)