EbrB

• Description: multidrug efflux transporter
  
  

Gene name	ebrB
Synonyms
Essential	no
Product	multidrug efflux transporter
Function	multidrug resistance
Gene expression levels in SubtiExpress: ebrB
Interactions involving this protein in SubtInteract: EbrB
MW, pI	12 kDa, 6.925
Gene length, protein length	351 bp, 117 aa
Immediate neighbours	ymaD, ebrA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, resistance against toxins/ antibiotics, membrane proteins

The gene

Basic information

• Locus tag: BSU17290

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): EbrA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: EbrA-EbrB PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: O31791

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ebrB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Zhongge Zhang, Che Ma, Owen Pornillos, Xia Xiu, Geoffrey Chang, Milton H Saier
Functional characterization of the heterooligomeric EbrAB multidrug efflux transporter of Bacillus subtilis.
Biochemistry: 2007, 46(17);5218-25
[PubMed:17417881] [WorldCat.org] [DOI] (P p)