PlsC

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Gene name plsC
Synonyms yhdO
Essential yes PubMed
Product acyl-ACP:1-acylglycerolphosphate acyltransferase
Function biosynthesis of phospholipids
Gene expression levels in SubtiExpress: plsC
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis
MW, pI 21 kDa, 9.976
Gene length, protein length 597 bp, 199 aa
Immediate neighbours yhdN, yhdP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YhdO context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PlsC expression.png




























Categories containing this gene/protein

biosynthesis of lipids, general stress proteins (controlled by SigB), essential genes, membrane proteins

This gene is a member of the following regulons

FapR regulon, SigB regulon

The gene

Basic information

  • Locus tag: BSU09540

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Luciana Paoletti, Ying-Jie Lu, Gustavo E Schujman, Diego de Mendoza, Charles O Rock
Coupling of fatty acid and phospholipid synthesis in Bacillus subtilis.
J Bacteriol: 2007, 189(16);5816-24
[PubMed:17557823] [WorldCat.org] [DOI] (P p)

Ayako Nishibori, Jin Kusaka, Hiroshi Hara, Masato Umeda, Kouji Matsumoto
Phosphatidylethanolamine domains and localization of phospholipid synthases in Bacillus subtilis membranes.
J Bacteriol: 2005, 187(6);2163-74
[PubMed:15743965] [WorldCat.org] [DOI] (P p)

Gustavo E Schujman, Luciana Paoletti, Alan D Grossman, Diego de Mendoza
FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis.
Dev Cell: 2003, 4(5);663-72
[PubMed:12737802] [WorldCat.org] [DOI] (P p)