YtpQ

From SubtiWiki
Revision as of 10:43, 1 August 2012 by Jstuelk (talk | contribs)
Jump to: navigation, search
  • Description: unknown

Gene name ytpQ
Synonyms
Essential no
Product unknown
Function maybe involved in iron homeostasis
MW, pI 30 kDa, 5.3
Gene length, protein length 807 bp, 269 aa
Immediate neighbours ytpR, ytpP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtpQ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YtpQ expression.png















Categories containing this gene/protein

acquisition of iron, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

Spx regulon

The gene

Basic information

  • Locus tag: BSU29830

Phenotypes of a mutant

  • derepression of the Fur and PerR regulons PubMed
  • elevated oxidative protein damage upon exposure of the cells to methylglyoxal PubMed
  • the spx ytpQ doulbe mutant shows reduced growth in minimal medium and hypersensitivity to methylglyoxal PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: UPF0354 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Peter Zuber, Shefali Chauhan, Praseeda Pilaka, Michiko M Nakano, Sairam Gurumoorthy, Ann A Lin, Skye M Barendt, Bui Khanh Chi, Haike Antelmann, Ulrike Mäder
Phenotype enhancement screen of a regulatory spx mutant unveils a role for the ytpQ gene in the control of iron homeostasis.
PLoS One: 2011, 6(9);e25066
[PubMed:21949854] [WorldCat.org] [DOI] (I p)