TagO

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  • Description: teichoic acid linkage unit synthesis

Gene name tagO
Synonyms yvhI
Essential yes PubMed
Product teichoic acid linkage unit synthesis
Function biosynthesis of teichoic acid
MW, pI 39 kDa, 10.424
Gene length, protein length 1074 bp, 358 aa
Immediate neighbours tagV, tuaH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TagO context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TagO expression.png
























Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, essential genes, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU35530

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: UDP-N-acetyl-D-glucosamine + undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-undecaprenol (according to Swiss-Prot)
  • Protein family: glycosyltransferase 4 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Alex Formstone, Rut Carballido-López, Philippe Noirot, Jeffery Errington, Dirk-Jan Scheffers
Localization and interactions of teichoic acid synthetic enzymes in Bacillus subtilis.
J Bacteriol: 2008, 190(5);1812-21
[PubMed:18156271] [WorldCat.org] [DOI] (I p)

Blazenka Soldo, Vladimir Lazarevic, Dimitri Karamata
tagO is involved in the synthesis of all anionic cell-wall polymers in Bacillus subtilis 168.
Microbiology (Reading): 2002, 148(Pt 7);2079-2087
[PubMed:12101296] [WorldCat.org] [DOI] (P p)