Tdh

• Description: L-threonine dehydrogenase
  
  

Gene name	tdh
Synonyms
Essential	no
Product	L-threonine dehydrogenase
Function	threonine utilization
Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr
MW, pI	36 kDa, 6.061
Gene length, protein length	1041 bp, 347 aa
Immediate neighbours	spoVS, kbl
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

utilization of amino acids

The gene

Basic information

• Locus tag: BSU16990

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: L-threonine + NAD⁺ = L-2-amino-3-oxobutanoate + NADH (according to Swiss-Prot)

• Protein family: zinc-containing alcohol dehydrogenase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 2DQ4 (from Thermus thermophilus, 47% identity, 63% similarity)

• UniProt: O31776

• KEGG entry: [2]

• E.C. number: 1.1.1.103

Expression and regulation

• Operon:

• Expression browser: tdh PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: